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KMID : 1157520210170010006
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International Journal of Clinical Preventive Dentistry
2021 Volume.17 No. 1 p.6 ~ p.11
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Antibiotic Effects of a Natural Extracts Mouthwash
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Hwang Se-Hyun
Hwang In-Chul
Lee Ji-Young
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Abstract
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Objective: Oral mouthwash is widely used in effective management of periodontal disease prevention, plaque removal, and bad breath removal. Commercially available oral mouthwash is a chemical substance that is likely to cause side effects, and significant research on natural substances is being conducted. In this study, a safe natural extracts mouthwash was developed and compared with Listerine, which has the largest market share, to confirm antibacterial activity.
Methods: In order to evaluate the antibacterial effects of natural mouthwash Natura-A, a natural extracts extracted from 30 kinds of plants and aquatic products, with the positive control Listerine, oral samples of 10 college students in their 20s for each group were analyzed using the polymerase chain reaction (PCR) technique for strain and concentration of 18 species of oral bacteria.
Results: The antibacterial effects of Listerine and Natura-A against Agregatibacter actinomytans, Tannerella forsythia, Treponema denticola, Parvimonas micra, Campylobacter rectus, Eubacterium nodatum, Eikenella corrodens, Streptococcus mutans., Streptoccuc sobrinus, Lactobacillus casei, Staphylococcus aureus, Enteroccus faecalis, and Actinomyces viscosus apeared to be excellent. For Prevotella intermedia, Prevotella nigrescens, Streptococcus mitis, Fusobacterium nucletum, and Porphyromonas gingivals showed good antibacterial action.
Conclusion: We suggest that Natura-A has an excellent inhibitory effect on oral microbes compared to Listerine and then that this natural extracts mouthwash can be used effectively to prevent oral diseases including dental caries and periodontal diseases safely in the long term without side effects.
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KEYWORD
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mouthwash, antibiotic, Listerine, anti-bacterial, extract
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